Amazing, but overwhelming.
This is a must when you come to room. Everything there is beautiful. It is so huge that if you don't know where you are going you could spend all day lost. So I recommended doing a tour. The Viator one we did was great. Also make sure you skip the line, because it would take so long. The Sistine Chapel really was amazing. I recommend that ladies bring a scarf, because it is really hot, but you need to have you're solders covered. Don't miss it, but don't spend more than 3 hours in it.