Nice Hampton, but don't expect peace and quiet!
Stayed at the Buffalo Hampton over Labor day with a spouse and small child. Hotel is beautiful, and as noted in other reviews, it has been completely renovated. The rooms and pool are the nicest I have ever seen at a Hampton Inn.
The downside: during our first night (a Friday), about 10pm the noise and smoke started becoming an issue. The hotel floor we were on was non-smoking, but guest were allowed to smoke unchecked. The downtown are near the hotel is a prime bar spot, and guest of the hotel (and non-guests) poor into and out of the hotel all night long. Yelling, fighting, music, etc. was the norm from 10pm until 4am when the police were called. Hampton security kicked many of the guests on our floor out of the hotel with reports of guest being passed out in pools of their own vomit, stolen passports, and fights.
I really feel for the security guard who had to resort to screaming at guests as he escorted them out, bordering on a fist-fight with him. The staff was apologetic, but they really have no choice but to rent rooms to anyone who pays for one. The second night was a little quieter, but a wedding party took over most of the floor and came and went while drunk throughout the night. Noise was the main issue.
Summary: the Hampton Inn downtown is a very nice hotel. However, with the amount of wear and tear (and vomit and smoke) that this lovely hotel is experiencing every weekend, it likely won't stay nice for long. I paid good money for two nights and got very little sleep, so I won't be back again.